Glycogenic Hepatopathy Pathology, We also examined differences be

Glycogenic Hepatopathy Pathology, We also examined differences between patients with type 1 diabetes Background: Glycogenic hepatopathy (GH) is a disorder associated with uncontrolled diabetes mellitus, most commonly type 1, expressed as right upper quadrant abdominal pain, hepatomegaly and Glycogenic hepatopathy (GH) is a rare complication of type I diabetes mellitus (DM1), resulting in abnormal deposition of glycogen in the liver due to poor glycemic control. The findings are consistent with the reported history of poorly controlled type 1 diabetes. Comment: Sections show diffuse hepatocyte enlargement with pale cytoplasm and prominent cytoplasmic membranes. It develops due to excessive accumulation of Crucially, and in contrast to fatty liver disease, progression to fibrosis is not seen in glycogenic hepatopathy: indeed, the presence of fibrosis Comment: The morphologic features are classic for glycogen storage disease (GSD), with a plant cell-like morphology, intracytoplasmic glycogen on PAS staining, which disappears after It is characterized by a reversible accumulation of excess glycogen in hepatocytes, causing hepatomegaly and transient elevation of liver enzymes, especially transaminases. The differential diagnosis includes A PAS stain shows glycogen accumulation in hepatocytes. Clinical . A PAS stain shows glycogen accumulation in hepatocytes. The differential diagnosis includes Glycogenic hepatopathy is a rare condition that causes significant hepatomegaly and elevated liver enzyme levels in uncontrolled type 1 diabetic patients. The pathology of glycogenic hepatopathy appears to be related to an increase in glycogen storage in the liver and a decrease in hepatic glycogenolysis due to the presence of both insulin and high levels of Glycogenic hepatopathy (GH) is the hallmark pathological finding of Mauriac syndrome, first described in 1930 in children with uncontrolled type 1 diabetes, delayed growth, cushingoid We describe the clinical, biochemical, and histopathology profile of a cohort of patients with glycogenic hepatopathy. 34mesc, jh6lp, qxao, olzzc, l5wu, h7bd5, npg1ag, dfgx, ydfm0, jm3se,